
The Orlistat capsule targets fat in your digestive system, working to stop you absorbing as much of the fat in your food as you usually would. This helps reduce calorie intake while promoting healthier eating habits.
Blocks around 25–30% of dietary fat from being absorbed
Manufacturer-sourced medication
Supported by clinical expertise and monthly check-ins
No hidden fees (pay-as-you-go)
Orlistat is a weight loss medication that works by blocking the absorption of dietary fat in your digestive system. It's designed for adults who are overweight or obese, especially those with weight-related health conditions.

Take one 60mg capsule with water during or within one hour of a main meal that contains fat. Do not take more than three capsules per day. Because it works by blocking the absorption of dietary fat, it's only effective when taken alongside meals that contain fat.
For best results and fewer side effects: limit your dietary fat to about 30% of your total calories per meal, distribute your fat intake evenly across meals, and avoid very high-fat meals to reduce side effects like oily stools or gastrointestinal discomfort.
Like any medication, Orlistat may cause side effects. The most common are gastrointestinal: oily or fatty stools, increased, urgent or frequent bowel movements, flatulence with oily discharge, and abdominal pain or diarrhoea. Other effects may include headaches, urinary infections, and low blood sugar in people with type 2 diabetes.
Orlistat is a prescription weight-loss medication suitable for adults.
During the consultation stage we’ll ask you for more specific information to ensure Wegovy is the right option for you.
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To assess your suitability and kick-start your journey, complete our questionnaire which takes approx 3 mins.
Phlo's prescribing pharmacists review and individually assess your treatment suitability using their extensive knowledge and clinical experience.
Once approved and dispensed, we’ll securely deliver your treatment using our free Royal Mail Tracked 24 option.
Explore our FAQs to find out more about this safe, no-surgery weight loss solution. Make sure you also read the Patient Information Leaflet that comes with your treatment.
Orlistat is a weight loss medication that works by blocking the absorption of dietary fat in your digestive system. It's designed for adults who are overweight or obese, especially those with weight-related health conditions.
Orlistat inhibits the enzyme lipase in your digestive tract, which breaks down fat. This prevents about 25–30% of the fat you consume from being absorbed, allowing it to pass naturally through your system.
Orlistat is suitable for adults with a BMI of 28 or higher, subject to a clinical assessment of your medical history during your consultation.
Take one 60mg capsule with water during or within one hour of a main meal that contains fat. Do not take more than three capsules per day. It only works alongside meals that contain fat.
Limit your dietary fat to about 30% of your total calories per meal, spread your fat intake evenly across meals, and avoid very high-fat meals to reduce side effects such as oily stools or digestive discomfort.
The most common side effects are gastrointestinal — oily or fatty stools, more frequent or urgent bowel movements, flatulence with oily discharge, and abdominal discomfort or diarrhoea. Other effects can include headaches, urinary infections, and low blood sugar in people with type 2 diabetes.